Patent Contents	Application country / Patent number
Cell death inducing agent of prostate cancer cell using REIC / Dkk-3 gene	Japan / 4838236 USA / 8658611
Partial fragment of REIC gene and cancer therapeutic agent containing said fragment	Japan / 5662534 USA / 9475865 Germany · France · UK / 2508606
Cancer cell death inducing agent having anticancer agent enhancing action in anticancer drug-resistant cancer	Japan / 5279235 China / ZL200880122369.2
A pharmaceutical composition for inducing dendritic cell-like differentiation from monocytes and for treating or preventing cancer which enhances anticancer immunity activity	China / ZL20098080116783.7 India / 287896
Malignant mesothelioma therapeutic agent and immunostimulating agent	Japan / 5551593 USA / 8658612 Germany · France · UK / 2327779 China / ZL200980136054.8
Gene expression upregulation system and vector	Japan / 5697042 USA / 9493776 Germany · France · UK / 2508603 China / ZL201080061897.9 Korea / 10-1752941 Australia / 2010322723 India / 308132 Canada / 2781332 Russia / 2577971 Israel / 219882
Partial region polypeptide of REIC protein	Japan / 5936129 USA / 9644013 Germany · France · UK / 2589658 China / ZL201180041601.1
REIC expressing adenoviral vector	Japan / 6014029 USA / 9222107 Germany · France · UK / 2716756 Taiwan / I 545196
Conditionally replicating adenovirus to express REIC gene	Japan / 6566214 USA / 10071126 Germany · France · UK / 3150706 China / ZL201580027897.X Korea / 10-2365331
Monitoring for cancer treatment using a specific antibody against REIC/Dkk-3 protein	Japan / 6975424 USA / 10782296 China / ZL201680056079.7
A combination therapy using REIC/Dkk-3 gene and a checkpoint inhibitor	Japan / 6803619 USA / 11484592 Germany · France · UK / 3400024 Australia / 2017205538 Canada / 3009883 Russia / 2748231,2767997 Israel / 260185
A combination therapy for treatment of thoracic cancer using Ad-REIC/Dkk-3 and a checkpoint inhibitor	Japan / 7386553

As of April 1, 2024